Microsporidia are a large group of obligate intracellular parasites. In this study, a label-free electrochemical genosensor was developed to detect Enterocytozoon bieneusi using specific probe and electrode substrate, Mxene-Ti3C2/AuNPs/PDA. A 5' thiol-modified DNA probe, targeting 16S like ribosomal RNA (rRNA) gene of E. bieneusi, was designed. The Ti3C2-AuNPs-PDA nanocomposite was synthesized.

Cancer incidence is rising globally, particularly in aging populations. Understanding the genetic, cellular, and molecular mechanisms underlying cancer is crucial for developing effective interventions. Dead-end protein 1 (DND1), an RNA-binding protein, plays a pivotal role in germ cell regulation and tumorigenesis.

In this study, we developed composite materials based on porous carbon doped with nitrogen and sulfur heteroatoms and integrated with ceria, targeting applications in high-performance supercapacitors.

BACKGROUND The role of amino acids and glycosidic compounds was investigated as edible and potential compatible stabilizing additives against Aspergillus oryzae alpha-amylase (AOA) inactivation and amorphous aggregation.

Early and timely disease diagnosis is crucial for effective treatment and improved clinical outcomes. Antibodies and their fragments are among the most widely used affinity reagents in point-of-care (POC) assays because of their target specificity and affinity.

The increasing prevalence of diabetes mellitus necessitates the development of advanced glucose-monitoring systems that are non-invasive, reliable, and capable of real-time analysis. Wearable electrochemical biosensors have emerged as promising tools for continuous glucose monitoring (CGM), particularly through sweat-based platforms.

The rapidly advancing field of microfluidics has significantly transformed diagnostics and pharmaceutical industries by enabling precise control and analysis of fluids at the microscale.

In this study, nitrogen-doped porous carbon materials derived from Azo-bridged calix[4]resorcinarene porous organic polymer were synthesized via pyrolysis at various temperatures. Notably, this work represents the first successful fabrication of nitrogen-doped carbon materials utilizing the Azo group (N=N) as a nitrogen source.

This study explores the potential of hemoglobin-capped green-synthesized carbon dots (g-CD) as a biosensor for the specific detection of cholesterol. The CDs, synthesized using an environmentally friendly and convenient microwave green approach, derived from Wood Extract of Wild Cherry Shrub and utilizing hemoglobin as a capping agent, offer promising characteristics for cholesterol detection.

Aromatic compounds are known anti-amyloid aggregates. Their effect on amorphous aggregates of proteins is, however, less studied. We chose aromatic amino acids Trp, Tyr, and Phe, as well as another known stabilizer (i.e. Arg), as potential compatible solvents to be tested on Bacillus amyloliquefaciens alpha-amylase (BAA).