Development and synthesis of DNA-based label-free electrochemical biosensor for detection of Enterocytozoon bieneusi using screen-printed gold electrode
Microsporidia are a large group of obligate intracellular parasites. In this study, a label-free electrochemical genosensor was developed to detect Enterocytozoon bieneusi using specific probe and electrode substrate, Mxene-Ti3C2/AuNPs/PDA. A 5' thiol-modified DNA probe, targeting 16S like ribosomal RNA (rRNA) gene of E. bieneusi, was designed. The Ti3C2-AuNPs-PDA nanocomposite was synthesized.
Dead-End protein expression, function, and mutation in cancer: a systematic review
Cancer incidence is rising globally, particularly in aging populations. Understanding the genetic, cellular, and molecular mechanisms underlying cancer is crucial for developing effective interventions. Dead-end protein 1 (DND1), an RNA-binding protein, plays a pivotal role in germ cell regulation and tumorigenesis.
Preparation of N-doped carbon material derived from porous organic polymer as an active center to growth nickel cobalt phosphide for high-performance supercapacitors
In this study, nitrogen-doped porous carbon materials derived from Azo-bridged calix[4]resorcinarene porous organic polymer were synthesized via pyrolysis at various temperatures. Notably, this work represents the first successful fabrication of nitrogen-doped carbon materials utilizing the Azo group (N=N) as a nitrogen source.
Hemoglobin-Capped carbon dots synthesized via microwave green approach as a biosensor for specific cholesterol detection
This study explores the potential of hemoglobin-capped green-synthesized carbon dots (g-CD) as a biosensor for the specific detection of cholesterol. The CDs, synthesized using an environmentally friendly and convenient microwave green approach, derived from Wood Extract of Wild Cherry Shrub and utilizing hemoglobin as a capping agent, offer promising characteristics for cholesterol detection.
Phenylalanine as an effective stabilizer and aggregation inhibitor of Bacillus amyloliquefaciens alpha-amylase
Aromatic compounds are known anti-amyloid aggregates. Their effect on amorphous aggregates of proteins is, however, less studied. We chose aromatic amino acids Trp, Tyr, and Phe, as well as another known stabilizer (i.e. Arg), as potential compatible solvents to be tested on Bacillus amyloliquefaciens alpha-amylase (BAA).
How biomimetic nanofibers advance the realm of cutaneous wound management: The state-of-the-art and future prospects
انتشار مقاله در حوزه مهندسی مواد در مجله معتبر با ضریب تاثیر بالا نتایج یک مقاله مروری با همکاری پژوهشگران مرکز تحقیقات بیوسنسور پژوهشگاه علوم غدد و متابولیسم دانشگاه علوم پزشکی تهران، دانشگاه آزاد واحد علوم تحقیقات، دانشگاه صنعتی شریف، دانشگاه بارسلونا، و دانشگاه فلوریدای مرکزی، در حوزه کاربرد نانوالیاف بیومیمتیک در بهبود زخم و بازسازی پوست در مجله معتبر Progress in Materials Science با ضریب تاثیر ۳۷/۴ و نمره ارجاعات ۶۷/۵ منتشر شد. این مقاله به مروری بر پیشرفت‌ها و روش های نوین در طراحی مواد نانو فیبری بیومیمتیک با پتانسیل بالا برای بهبود زخم و بازسازی پوست می‌پردازد.
Mercury (II) sensing using a simple turn-on fluorescent graphene oxide based aptasensor in serum and water samples
Abstract A simple, highly sensitive, and selective fluorometric aptasensing platform based on aptamer and graphene oxide (GO) is proposed for the determination of mercury (II) ion (Hg2+). In the designed assay, two aptamer probes, a carboxy-fluorescein (FAM) labeled aptamer (aptamer A) and its complementary (aptamer B) with partial complement containing several mismatches and GO as the quencher were used.
Emergence of sweet ligand-protein complexes from seemingly non-sweet conformations
Sweet taste perception starts from the interaction of a sweet molecule with residues of the sweet taste receptor (STR). Yet, how the perception of sweet taste emerges from this interaction is still not clear. Here, we reveal a potential mechanism in the initial stages of this cascade.
Electrochemical Sensing Based on Nanofibers Modified Electrodes for Application in Diagnostic, Food and Waste Water Samples
Electrochemical sensors and biosensors are today important analytical and monitoring tools in various fields, from agriculture and the food industry to environmental and biomedical/pharmaceutical applications.
Structural insights into the pathogenicity of point mutations in human acyl-CoA dehydrogenase homotetramers
Acyl-CoA dehydrogenase deficiency (ACAD) is an inherited and potentially fatal disorder with variable clinical symptoms. The relationship between pathogenicity and deleterious point mutations is investigated here in ACAD structures of short (SCAD) and medium-chain (MCAD) types.
