Nitrogen and sulfur co-doped carbon quantum dots fluorescence quenching assay for detection of mercury (II)
Mercury is a highly toxic and potentially bioaccumulative heavy metal ion that can cause severe health problems in humans even at very low concentrations.
A Label-Free Electrochemical Aptasensor Based on Screen Printed Carbon Electrodes With Gold Nanoparticles-Polypyrrole Composite for Detection of Cardiac Troponin I
Cardiac troponin I (cTnI) is a specific biomarker in the diagnosis of acute myocardial infarction (AMI). In this study, a label-free electrochemical aptasensor was developed for the detection of cTnI using an aptamer probe and conductive polypyrrole (PPy)-gold nanoparticles (AuNPs) as electrode substrate.
Application of polysaccharide biopolymers as natural adsorbent in sample preparation
Preparing samples for analyses is perhaps the most important part to analyses. The varied functional groups present on the surface of biopolymers bestow them appropriate adsorption properties.
Chemical Modification of the Amino Groups of Human Insulin: Investigating Structural Properties and Amorphous Aggregation of Ace
The efficacy of human recombinant insulin can be affected by its aggregation. Effects of acetylation were observed on insulin structure, stability, and aggregation at 37 and 50 °C and pH of 5.0 and 7.4 with the use of spectroscopy, circular dichroism (CD), dynamic light scattering (DLS), and atomic force microscopy (AFM)
PEGylated PAMAM dendrimers as eptifibatide nanocarriers: An atomistic view from molecular dynamics simulations
Acetylation and PEGylation can decrease cytotoxicity, improve biocompatibility, and reduce the rate of PAMAM dendrimers elimination from systemic circulation. However, there is scarce information on the microstructure and drug loading capacity of PEGylated dendrimers at atomic level.
Adverse effects of polystyrene nanoplastic and its binary mixtures with nonylphenol on zebrafish nervous system: From oxidative stress to impaired neurotransmitter system
Micro(nano)plastics generally co-exist with other chemicals in the environment, resulting in inevitable interaction and combined toxic effects on biota. Nevertheless, little is known regarding the interaction of nanoplastics (NPs) with other co-occurring insults. Hereby, we investigated single and combined effects of chronic exposure (45 days) to polystyrene nanoplastic particulates (PS-NPs) and nonylphenol (4-NP) on zebrafish nervous system.
Toward waterborne protozoa detection using sensing technologies
Drought and limited sufficient water resources will be the main challenges for humankind during the coming years. The lack of water resources for washing, bathing, and drinking increases the use of contaminated water and the risk of waterborne diseases.